Abstract

The possibility of the chromatographic separation of isomeric nitroanilines and fluorine-substituted analogues using porous coordination polymers [Al(OH)(Fum)]_n (I) (Fum^2– is trans-1,2-ethylenedicarboxylic acid anion), [Al(OH)(Bdc)]_n (II) (Bdc^2– is 1,4-benzenedicarboxylic acid anion), [Cu₃(Btc)₂(H₂O)₃] (III) (Btc^3– is 1,3,5-benzenetricarboxylic acid anion), and [Cr₃(O)(OH)(H₂O)₂(Bdc)₃] (IV) as stationary phases in a mixture of nonpolar solvents is studied. The separation of the amines is achieved only in the case of [Al(OH)(Fum)]_n. Possible relationships of the separation factors of the amines to the sizes of the molecules, polarity, and lipophilicity are examined. Among the factors considered, only the difference between the values of lipophilicity exerts a noticeable effect on the efficiency.

中文翻译：

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液相色谱固定相羧酸根多孔配位聚合物的结构对苯胺衍生物分离效率的影响

摘要

使用多孔配位聚合物[Al（OH）（Fum）] _n（I）（Fum ^2–是反式-1,2-亚乙基二羧酸阴离子）进行色谱分离异构体硝基苯胺和氟取代的类似物的可能性，[Al（ OH）（Bdc）] _n（II）（Bdc ^2–是1,4-苯二甲酸阴离子），[Cu ₃（Btc）₂（H ₂ O）₃ ]（III）（Btc ^3–是1,3， 5-苯三羧酸阴离子）和[Cr ₃（O）（OH）（H ₂ O）₂（Bdc）₃ ]（IV）作为非极性溶剂混合物中的固定相进行了研究。仅在[Al（OH）（Fum）] _n的情况下才能实现胺的分离。检查了胺的分离因子与分子大小，极性和亲脂性的可能关系。在考虑的因素中，只有亲脂性值之间的差异才对效率产生显着影响。