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Effect of banana pulp dietary fibers on metabolic syndrome and gut microbiota diversity in high-fat diet mice.
Journal of Food Biochemistry ( IF 4 ) Pub Date : 2020-07-14 , DOI: 10.1111/jfbc.13362
Guohua Wei 1, 2 , Yong Ye 1, 2 , Xiang Yan 1, 2 , Xingyu Chao 1, 2 , Fan Yang 1, 2 , Mengyang Wang 1, 2 , Wencheng Zhang 1, 2 , Chuanxun Yuan 1, 2 , Qingmei Zeng 1, 2
Affiliation  

Banana (Musa nana Lour.) have the effect of anti‐obesity and lipid modulating properties. However, the influences of banana pulp dietary fibers (BP‐DF) on metabolic syndrome (MetS) and gut microbiota (GM) are unknown. In this research, we explore a novel strategy for dietary BP‐DF on attenuation of lipid metabolic disease, GM disorder, and associated mechanisms in high‐fat diet (HFD) mice. BP‐DF can strongly suppress on HFD caused body weight and epididymal fat mass gain, and significantly improved serum lipid profiles, liver lipid profiles, and intestinal function. BP‐DF also significantly improved fecal short‐chain fatty acids formation and fecal ammonia content. BP‐DF impacted the intestinal microorganism at all kinds of taxonomic levels by increasing the proportions of beneficial Lactobacillus, Bacteroidales _S24_7_group, and Alloprevotella and decreasing the disease or obesity associated Sutterella, Streptococcaceae, and Erysipelotrichaceae. The experiments show that BP‐DF may use as a functional ingredient for preventing obesity, MetS, and intestinal microorganism imbalance.

中文翻译:

香蕉果肉膳食纤维对高脂饮食小鼠代谢综合征和肠道菌群多样性的影响。

香蕉(Musa nana Lour。)具有抗肥胖和调脂作用。但是,香蕉果肉膳食纤维(BP-DF)对代谢综合征(MetS)和肠道菌群(GM)的影响尚不清楚。在这项研究中,我们探索了饮食BP-DF减轻脂代谢疾病,GM紊乱以及高脂饮食(HFD)小鼠相关机制的新策略。BP‐DF可以强烈抑制HFD引起的体重和附睾脂肪增加,并显着改善血清脂质谱,肝脂质谱和肠道功能。BP‐DF还可以显着改善粪便短链脂肪酸的形成和粪便氨含量。BP‐DF通过增加有益乳酸菌的比例在各种分类学水平上影响肠道微生物Bacteroidales _S24_7_group,Alloprevotella和减少相关的疾病或肥胖Sutterella,链球菌科,丹毒丝。实验表明BP‐DF可以用作预防肥胖,MetS和肠道微生物失衡的功能成分。
更新日期:2020-09-14
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