Colorectal cancer is highly incident worldwide and presents a health burden with elevated mortality rate despite prevention, detection, and treatment, mainly due to metastatic liver disease. Histological growth patterns of colorectal cancer liver metastases have emerged as a reproducible prognostic factor, with biological implications and therapeutic windows. Nonetheless, the histological growth patterns of colorectal cancer liver metastases are only known after pathological examination of a liver resection specimen, thus limiting the possibilities of pre-surgical decision. Predicting the histological growth pattern of colorectal cancer liver metastases would provide valuable information for patient-tailored medicine. In this article, we perform a review of the histological growth patterns and their implications, with a focus on the possibilities for their prediction.

结直肠癌在世界范围内的发病率很高，尽管预防、检测和治疗，但主要是由于转移性肝病，导致健康负担升高，死亡率升高。结直肠癌肝转移的组织学生长模式已成为可重复的预后因素，具有生物学意义和治疗窗口。尽管如此，结直肠癌肝转移的组织学生长模式只有在对肝切除标本进行病理学检查后才能知道，从而限制了术前决策的可能性。预测结直肠癌肝转移的组织学生长模式将为患者量身定制医学提供有价值的信息。在本文中，我们对组织学生长模式及其影响进行了回顾，