Mosquitoes are the main vector of multiple diseases worldwide and transmit viral (malaria, chikungunya, encephalitis, yellow fever, as well as dengue fever), as well as bacterial diseases (tularemia). To manage the outbreak of mosquito populations, various management programs include the application of chemicals, followed by biological and genetic control. Here we aimed to focus on the role of bacterial pathogenesis and molecular tactics for the management of mosquitoes and their vectorial capacity. Bacterial pathogenesis and molecular manipulations have a substantial impact on the biology of mosquitoes, and both strategies change the gene expression and regulation of disease vectors. The strategy for genetic modification is also proved to be excellent for the management of mosquitoes, which halt the development of population via incompatibility of different sex. Therefore, the purpose of the present discussion is to illustrate the impact of both approaches against the vectorial capacity of mosquitoes. Moreover, it could be helpful to understand the relationship of insect-pathogen and to manage various insect vectors as well as diseases.

蚊子是世界范围内多种疾病的主要媒介，并传播病毒（疟疾，基孔肯雅热，脑炎，黄热病和登革热）以及细菌性疾病（Tularemia）。为了控制蚊子的爆发，各种管理计划包括化学药品的施用，然后进行生物和基因控制。在这里，我们旨在集中于细菌发病机理和分子策略对蚊子的控制及其媒介能力的作用。细菌的发病机理和分子操作对蚊子的生物学有重大影响，并且这两种策略都会改变基因表达和疾病载体的调控。事实证明，基因改造策略对于蚊子的控制非常有效，通过不同性别的不兼容而阻止了人口的发展。因此，本讨论的目的是说明两种方法对蚊子矢量能力的影响。此外，了解昆虫病原体的关系并管理各种昆虫媒介以及疾病可能会有所帮助。