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Management of antiepileptic drug-induced nutrition-related adverse effects.
Neurological Sciences ( IF 2.7 ) Pub Date : 2020-07-14 , DOI: 10.1007/s10072-020-04573-5
Maryam Safahani 1 , Hadi Aligholi 2, 3 , Ali A Asadi-Pooya 2, 4
Affiliation  

Although antiepileptic drugs (AEDs) are mainstay of the treatment of epilepsy, they are associated with significant adverse effects. The present study reviews the adverse effects of AEDs on some of the nutrition-related issues, including bone health, body weight, glucose and lipid metabolism, vitamin homeostasis, antioxidant defense system, and pregnancy. This paper also provides some nutritional recommendations for people with epilepsy. Patients with epilepsy should be regularly evaluated with regard to their nutrition status and any possible nutritional problems. Daily intake of adequate amounts of all nutrients from various sources should be encouraged, especially for vulnerable groups such as children, adolescents, elderly, and pregnant women. When necessary, preventative or therapeutic supplementation with appropriate micronutrients could be helpful.

Graphical abstract



中文翻译:

处理抗癫痫药引起的营养相关不良反应。

尽管抗癫痫药(AED)是治疗癫痫症的主要手段,但它们仍具有明显的不良反应。本研究综述了AED对某些与营养有关的问题的不良影响,包括骨骼健康,体重,葡萄糖和脂质代谢,维生素体内稳态,抗氧化防御系统和怀孕。本文还为癫痫患者提供了一些营养建议。癫痫患者应定期评估其营养状况和任何可能的营养问题。应鼓励每天从各种来源摄入足够量的所有营养素,尤其是对于弱势群体,例如儿童,青少年,老年人和孕妇。必要时,

图形概要

更新日期:2020-07-14
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