Exploitation of potential extremophiles for bioremediation of xenobiotics compounds: a biotechnological approach,Current Genomics

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Exploitation of potential extremophiles for bioremediation of xenobiotics compounds: a biotechnological approach
Current Genomics ( IF 1.8 ) Pub Date : 2020-07-10 , DOI: 10.2174/1389202921999200422122253
Awadhesh Kumar Shukla ₁ , Amit Kishore Singh ₂

Affiliation

Microorganisms that are capable of live and adapt in hostile habitats of different environmental factors such as extremes temperature, salinity, nutrient availability and pressure are known as extremophiles. Exposure to xenobiotic compounds is global concern influencing the world population as a health hazard. Hence their removal is warranted using biological means that is very sustainable, potentially cost-effective and eco-friendly. Due to adaptation in extreme environments and unique defense mechanisms, they are receiving more attention for the bioremediation of the xenobiotic compounds. They possess robust enzymatic and biocatalytic systems that make them suitable for the effective removal of pollutants from the contaminated environment. Additionally, the extremophiles act as microfactories having specific genetic and biotechnological potential for the production of biomolecules. This mini review will provide an overview of microbial degradation metabolic pathways for bioremediation along with the molecular and physiological properties of diverse extremophiles from variety of habitats. Furthermore, the factors affecting the bioremediation process is also summarized.

中文翻译：

利用潜在的极端微生物对异生物质化合物进行生物修复：一种生物技术方法

能够在极端温度、盐度、营养供应和压力等不同环境因素的恶劣栖息地中生存和适应的微生物被称为极端微生物。接触外源性化合物是全球关注的问题，它影响世界人口作为一种健康危害。因此，必须使用非常可持续、具有潜在成本效益和生态友好的生物方法去除它们。由于对极端环境的适应和独特的防御机制，它们在异生化合物的生物修复方面受到越来越多的关注。它们拥有强大的酶促和生物催化系统，使其适用于有效去除受污染环境中的污染物。此外，极端微生物作为微型工厂，具有生产生物分子的特定遗传和生物技术潜力。这篇小型综述将概述用于生物修复的微生物降解代谢途径，以及来自各种栖息地的各种极端微生物的分子和生理特性。此外，还总结了影响生物修复过程的因素。

更新日期：2020-07-10

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