Shotgun metagenomic sequencing has improved our understanding of the human gut microbiota. Various DNA extraction methods have been compared to find protocols that robustly and most accurately reflect the original microbial community structures. However, these recommendations can be further refined by considering the time and cost demands in dealing with samples from very large human cohorts. Additionally, fungal DNA extraction performance has so far been little investigated.

中文翻译：

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用于宏基因组研究的粪便 DNA 提取方案评估。


鸟枪法宏基因组测序提高了我们对人类肠道微生物群的了解。对各种 DNA 提取方法进行了比较，以找到能够稳健且最准确地反映原始微生物群落结构的方案。然而，通过考虑处理来自非常大的人类群体的样本的时间和成本需求，可以进一步完善这些建议。此外，迄今为止，真菌 DNA 提取性能的研究还很少。