In this issue of Nature Metabolism, Mi and colleagues provide evidence that super-enhancers play a critical role in autosomal-dominant polycystic kidney disease (ADPKD) and show that CDK7 targeting provides a novel therapeutic option.

中文翻译：

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超级增强剂和CDK7可以解释多囊肾疾病中的代谢重编程：新的治疗靶点？

在本期《自然代谢》杂志中，Mi及其同事提供了证据，证明超级增强剂在常染色体显性遗传的多囊性肾病（ADPKD）中起着关键作用，并表明CDK7靶向提供了一种新颖的治疗选择。