ABSTRACT

Three hundred and ninety-seven primary- and secondary-care physicians were tested for the presence of IgG (and IgA) antibodies against SARS-coronavirus-2 with a commercially available ELISA. In 19 of 20 individuals with PCR-proven infection and only mild to moderate symptoms not requiring hospitalization positive IgG levels occurred within two to three weeks. Among the remaining 377 persons without clear-cut evidence of infection, unequivocally positive IgG antibodies were found in only one, showing a surprisingly low prevalence (0.3%, 95% CI: 0.01–1.5) in physicians with likely contacts with infected patients in a region highly affected by the pandemic (Tyrol, Austria).

摘要

用市售的ELISA测试了三百九十七名初级和二级保健医生的抗SARS冠状病毒2 IgG（和IgA）抗体的存在。在20名经PCR证实感染且只有不需要住院治疗的轻度至中度症状的患者中，有2-3人出现了IgG阳性。在其余377名没有明确感染证据的人中，只有一种人明确发现IgG抗体呈阳性，表明在可能与感染患者接触的医师中，其患病率异常低（0.3％，95％CI：0.01-1.5）。受大流行影响严重的地区（奥地利蒂罗尔州）。