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Nonthermal plasma as part of a novel strategy for vaccination
Plasma Processes and Polymers ( IF 2.9 ) Pub Date : 2020-07-13 , DOI: 10.1002/ppap.202000051
Hager Mohamed 1 , Rita A Esposito 1 , Michele A Kutzler 1 , Brian Wigdahl 1 , Fred C Krebs 1 , Vandana Miller 1
Affiliation  

Abstract Vaccination has been one of the most effective health intervention mechanisms to reduce morbidity and mortality associated with infectious diseases. Vaccines stimulate the body's protective immune responses through controlled exposure to modified versions of pathogens that establish immunological memory. However, only a few diseases have effective vaccines. The biological effects of nonthermal plasma on cells suggest that plasma could play an important role in improving efficacy of existing vaccines and overcoming some of the limitations and challenges with current vaccination strategies. This review summarizes the opportunities for nonthermal plasma for immunization and therapeutic purposes.

中文翻译:


非热等离子体作为疫苗接种新策略的一部分



摘要 疫苗接种已成为降低传染病发病率和死亡率的最有效的健康干预机制之一。疫苗通过受控地接触经过修饰的病原体来刺激人体的保护性免疫反应,从而建立免疫记忆。然而,只有少数疾病有有效的疫苗。非热等离子体对细胞的生物学效应表明,等离子体可以在提高现有疫苗的功效和克服当前疫苗接种策略的一些限制和挑战方面发挥重要作用。本综述总结了非热等离子体用于免疫和治疗目的的机会。
更新日期:2020-07-13
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