New and old adjuvants in allergen-specific immunotherapy: With a focus on nanoparticles.,Journal of Cellular Physiology

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New and old adjuvants in allergen-specific immunotherapy: With a focus on nanoparticles.
Journal of Cellular Physiology ( IF 4.5 ) Pub Date : 2020-07-13 , DOI: 10.1002/jcp.29941
Zhongtao Feng ₁ , Xin Yi ₁ , Jafar Hajavi ₂

Affiliation

Allergic diseases have remarkably increased in recent years. Nowadays, efforts for curing and management of these disorders are an important concern worldwide. Allergen‐specific immunotherapy (ASIT) has recently gained more attention as a means for the management of allergic diseases. Adjuvants or helper agents are materials applied for better stimulating and shifting of protective responses, and these belong to an extremely diverse collection of complexes. The main function of adjuvants includes acting as depot foundations, transferring vehicles, and immunostimulators. Immunostimulatory adjuvants have gained increasing attention for ASIT. In this regard, the present study provides a review of old and new adjuvants used in allergen immunotherapy.

中文翻译：

过敏原特异性免疫疗法中的新旧佐剂：以纳米颗粒为重点。

近年来，过敏性疾病显着增加。如今，治疗和管理这些疾病的努力是世界范围内的一个重要问题。过敏原特异性免疫疗法（ASIT）最近作为一种治疗过敏性疾病的手段受到了越来越多的关注。佐剂或辅助剂是用于更好地刺激和转移保护反应的材料，它们属于极其多样化的复合物集合。佐剂的主要功能包括作为贮库基础、转运载体和免疫刺激剂。免疫刺激佐剂越来越受到 ASIT 的关注。在这方面，本研究对过敏原免疫治疗中使用的新旧佐剂进行了回顾。

更新日期：2020-07-13

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