Landmark discoveries in cancer research improve clinical therapies. To bring these therapies to the right patients quickly and safely requires well-designed clinical trials. Harmony Turk of Cancer Cell and Sara Hamilton of Cell Reports Medicine spoke with Dr. Lillian Siu of Princess Margaret Cancer Center, Dr. Carl June of the University of Pennsylvania’s Perelman School of Medicine, and Dr. Patrick Ott of Dana-Farber Cancer Institute on improving the design of oncology clinical trials in the evolving landscape of precision medicine. Excerpts from this conversation are presented below, and the full conversation is available with the article online. Editor’s note: Some text was subsequently revised for clarity and conciseness.

癌症研究中具有里程碑意义的发现改善了临床疗法。为了将这些疗法快速，安全地带给合适的患者，需要精心设计的临床试验。癌细胞的和谐特克和细胞报告医学的萨拉·汉密尔顿与玛格丽特公主癌症中心的Lillian Siu博士，宾夕法尼亚大学佩雷​​尔曼医学院的Carl June博士以及达纳-法伯癌症研究所的Patrick Ott博士进行了会谈。在不断发展的精确医​​学领域中改进肿瘤临床试验的设计。下面提供了该对话的摘录，完整的对话可通过在线文章获得。编者注：为了清晰和简洁起见，随后对某些文本进行了修订。