Polyglycerol sebacate (PGS) scaffolds obtained using a leaching technique were modified with iodine-doped polypyrrole (PPy-I) in a plasma reactor in order to study the effect of exposure time on the cell viability of hDPSCs. SEM analysis showed the formation and growth of PPy-I particles as the exposure time was increased, while FTIR and XPS analysis revealed the presence of -NH- and N+ groups in the chemical composition of the surfaces, relating to the increase in the amount of PPY-I particles. The water contact angle measurements showed an increase in the scaffold’s hydrophilicity with greater exposure times which was also attributed to the rising of PPy-I particles. It was also observed that PPy-I promotes the rigidity of the treated PGS scaffolds. when in direct contact with treated PGS scaffolds, cell viability improved with respect to non-treated scaffolds, however only at shorter time exposures. Extracts of plasma-treated PGS scaffolds showed high cytotoxicity as the time exposure to plasma treatment was increased.

使用浸出技术获得的聚甘油癸二酸酯 (PGS) 支架在等离子体反应器中用掺碘聚吡咯 (PPy-I) 进行改性，以研究暴露时间对 hDPSCs 细胞活力的影响。SEM 分析表明，随着暴露时间的增加，PPy-I 颗粒的形成和生长，而 FTIR 和 XPS 分析表明，表面化学成分中存在 -NH- 和 N+ 基团，这与PPY-I 颗粒。水接触角测量表明支架的亲水性随着暴露时间的增加而增加，这也归因于 PPy-I 颗粒的上升。还观察到 PPy-I 提高了处理过的 PGS 支架的刚度。当与经过处理的 PGS 支架直接接触时，相对于未经处理的支架，细胞活力得到改善，但仅在较短的时间暴露下。随着暴露于血浆处理的时间增加，血浆处理的 PGS 支架的提取物显示出高细胞毒性。