A NiCo2S4@N/S–CeO2 composite as an electrocatalytic signal amplification label for aptasensing,Journal of Materials Chemistry C

当前位置： X-MOL 学术 › J. Mater. Chem. C › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

A NiCo2S4@N/S–CeO2 composite as an electrocatalytic signal amplification label for aptasensing
Journal of Materials Chemistry C ( IF 5.7 ) Pub Date : 2020-07-11 , DOI: 10.1039/d0tc02738c
Lele Li _{1,

2,

3,

4,

5} , Liwei Yang _{1,

2,

3,

4,

5} , Si Zhang _{1,

2,

3,

4,

5} , Yuping Sun _{1,

2,

3,

4,

5} , Fen Li _{1,

2,

3,

4,

5} , Tengteng Qin _{1,

2,

3,

4,

5} , Xiaoqiang Liu _{1,

2,

3,

4,

5} , Yanmei Zhou _{1,

2,

3,

4,

5} , Subbiah Alwarappan _{6,

7,

8,

9}

Affiliation

Herein, we designed a NiCo₂S₄@N/S–CeO₂ composite with amplified electrocatalytic oxygen reduction (OR) capability by the in situ growth of NiCo₂S₄ nanoparticles on CeO₂ nanospheres with simultaneous doping of nitrogen and sulfur. After optical characterization of the composite, it was then employed as the signal amplification label for constructing an electrochemical aptasensor. The composite provides a biocompatible and large surface platform to load biomolecules and retain their bioactivity. More importantly, the composite shows a comparable electrocatalytic OR capability similar to a commercial Pt/C catalyst and far better than CeO₂, attributed to the NiCo₂S₄ deposition and oxygen vacancies introduced by N and S doping. Furthermore, the Koutecky–Levich plots indicate a nearly four-electron transfer pathway of the ORR. The as-prepared aptasensor exhibited a highly sensitive and selective determination of a model analyte-sulfadimethoxine with a wide linear range of 0.05–180 nM, a low detection limit of 0.02 ± 0.0011 nM and good feasibility for real-sample detection. This work paved an effective way for the design of highly efficient electrocatalysts with bright prospects in bioanalytical applications.

中文翻译：

NiCo2S4 @ N / S–CeO2复合材料作为适体感觉的电催化信号放大标签

在本文中，我们设计了一种NiCo ₂ S ₄ @ N / S–CeO ₂复合材料，该复合材料通过在CeO ₂纳米球上原位生长NiCo ₂ S ₄纳米颗粒并同时掺杂氮和硫，具有增强的电催化氧还原（OR）能力。在对复合材料进行光学表征后，然后将其用作构建电化学适体传感器的信号放大标记。该复合材料提供了一种生物相容性大的表面平台，可装载生物分子并保持其生物活性。更重要的是，该复合材料显示出与市售Pt / C催化剂相似的电催化OR能力，并且远优于CeO ₂，归因于NiCo ₂ S _4的沉积和N和S掺杂引入的氧空位。此外，Koutecky-Levich图显示了ORR的近四电子转移途径。所制备的适体传感器对模型分析物-磺胺二甲嘧啶具有高灵敏度和选择性的测定，线性范围为0.05-180 nM，检测下限为0.02±0.0011 nM，在真实样品检测中具有良好的可行性。这项工作为在生物分析应用中具有广阔前景的高效电催化剂的设计铺平了一条有效途径。

更新日期：2020-08-05

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11