Abstract

One new coumarin (stercularin), along with eleven known compounds, was isolated for the first time from ethyl acetate fraction of Sterculia diversifolia. The structures of isolated compounds were characterized by spectroscopic techniques such as EIMS, ¹H-NMR and ¹³C-NMR. Compound 1 showed significant cytotoxicity by brine shrimp lethality assay (LD₅₀: 8.00 μg/ml) and PC-3 cell lines protocol (IC₅₀: 3.92 ± 0.20 μg/ml), respectively.

中文翻译：

---

来自Sterculia diversifolia的具有细胞毒性的化学成分

摘要

首次从Sterculia diversifolia 的乙酸乙酯级分中分离出一种新的香豆素 (stercularin)，以及 11 种已知化合物。分离化合物的结构通过光谱技术如 EIMS、¹ H-NMR 和¹³ C-NMR表征。化合物1 分别通过盐水虾致死率测定 (LD ₅₀ : 8.00 μg/ml) 和 PC-3 细胞系方案 (IC ₅₀ : 3.92 ± 0.20 μg/ml)显示出显着的细胞毒性。