Susceptibility to viral infection, development of immunity, response to treatment and patient clinical outcomes are all under the control of heritable factors in the host. In the context of the current SARS‐Cov‐2 pandemic, this review considers existing immunogenetic knowledge of virus‐immune system interactions. A major focus is to highlight areas in which work is required in order to improve understanding of antiviral immune responses and to move towards improved patient management.

中文翻译：

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SARS-CoV-2：免疫遗传学的战斗号角

对病毒感染的易感性、免疫力的发展、对治疗的反应和患者的临床结果都受到宿主遗传因素的控制。在当前 SARS-Cov-2 大流行的背景下，本综述考虑了病毒与免疫系统相互作用的现有免疫遗传学知识。主要重点是强调需要开展工作的领域，以提高对抗病毒免疫反应的理解并改善患者管理。