Non‐tuberculous mycobacteria (NTM) are ubiquitous environmental bacteria isolated from soil, surface waters, urban water supplies, and houses. The genetic susceptibility to NTM is an essential part of pathogenesis as discussed elsewhere. Recognition of bacterial components by pattern‐recognition receptors (PRRs) plays a major role in the immune response upon bacterial infections.

中文翻译：

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NOD2基因的Missense（p.Glu778Lys）和（p.Gly908Arg）变异与复发性肺非结核分枝杆菌感染有关。

非结核分枝杆菌（NTM）是从土壤，地表水，城市供水和房屋中分离的普遍存在的环境细菌。NTM的遗传易感性是发病机理的重要组成部分，如其他地方所讨论。模式识别受体（PRR）对细菌成分的识别在细菌感染的免疫反应中起主要作用。