In this work, we report on an integrated digital microfluidic system for precise sensing and automatic actuating droplets (ISPSAA) based on electrowetting on dielectric (EWOD). A feedback controller in the system is capable of locating, judging and controlling individual droplet independent of liquid composition. An integrated position sensor is capable of tracking the continuous displacement of a droplet between electrodes through the feedback of capacitance difference in real time, and thus improves the droplet control precision. Real-time droplet allocation and actuation have been achieved in a digital and precise way by combining the droplet sensing and driving functions. A defect electrode on the droplet transportation path can also be sensed and avoided in an intelligent way by adjusting corresponding electrodes and parameters to actuate the droplet to reach destination position based on the designed route with minimum number of actuated electrodes. Because of its portability, low cost, and adaptive functions, ISPSAA are helpful for further understanding and implementation of digital microfluidic systems for practical applications.

在这项工作中，我们报告了一种基于电介质上电润湿（EWOD）的，用于精确感测和自动驱动液滴（ISPSAA）的集成数字微流系统。系统中的反馈控制器能够独立于液体成分定位，判断和控制单个液滴。集成的位置传感器能够通过电容差的实时反馈来跟踪液滴在电极之间的连续位移，从而提高了液滴的控制精度。通过结合液滴传感和驱动功能，以数字化和精确的方式实现了实时液滴分配和驱动。通过基于最小数量的被致动电极的设计路线，通过调整相应的电极和参数以致动液滴以到达目的地位置，也可以以智能的方式感测和避免在液滴输送路径上的缺陷电极。由于其便携性，低成本和自适应功能，ISPSAA有助于进一步了解和实现用于实际应用的数字微流体系统。