We aim at encapsulating fragrances made of a variety of lipophilic species to slow down their diffusion. Our strategy is to develop capsules by polymerizing the water intermediate phase of an oil-in-water-in-oil double emulsion. In other terms, our system consists in a direct emulsion of fragrance (O1) in a water phase (W) containing monomer, initiator, and cross-linker. To obtain the double emulsion, this direct emulsion, stabilized by a hydrophilic surfactant, is itself dispersed in an external lipophilic solvent used in perfumery (O2) and stabilized by a lipophilic surfactant. Polymerization of the intermediate water phase aims at obtaining a 3D network. Differently from nowadays-proposed capsules, this strategy allows polymerization only taking place in the water phase rather in the phase containing the fragrance. Moreover, the obtained 3D network is supposed to play the role of an effective barrier limiting the diffusion of the inner lipophilic species towards either the external solvent or air. Such an approach implies the combination of a formulation step to elaborate the double emulsion using two antagonistic surfactants, a hydrophilic one and a lipophilic one, and of the polymerization of the intermediate phase. Insertion of the polymerizable species in the double emulsion shall not destabilize it. Some monomers exhibiting interfacial affinity and interfering with the formulation of the double emulsion have to be avoided. By varying the nature of the monomers and the cross-linker to monomer ratio, capsules with high encapsulation efficiencies and with various mechanical properties have been obtained. Graphical abstract Graphical abstract

中文翻译：

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双乳液基聚合物香精胶囊的研制

我们的目标是封装由各种亲脂性物质制成的香料，以减缓它们的扩散。我们的策略是通过聚合油包水包油双乳液的水中间相来开发胶囊。换句话说，我们的系统包括香料 (O1) 在含有单体、引发剂和交联剂的水相 (W) 中的直接乳液。为了获得双乳液，这种由亲水表面活性剂稳定的直接乳液本身分散在香料（O2）中使用的外部亲油溶剂中，并由亲油表面活性剂稳定。中间水相的聚合旨在获得 3D 网络。与现在提出的胶囊不同，这种策略允许聚合仅在水相中而不是在含有香料的相中发生。而且，获得的 3D 网络应该发挥有效屏障的作用，限制内部亲脂性物质向外部溶剂或空气的扩散。这种方法意味着将使用两种拮抗性表面活性剂（亲水性表面活性剂和亲脂性表面活性剂）和中间相聚合制成双乳液的配制步骤相结合。双乳液中可聚合物质的插入不应使其不稳定。必须避免一些表现出界面亲和力和干扰复乳液配方的单体。通过改变单体的性质和交联剂与单体的比例，获得了具有高封装效率和各种机械性能的胶囊。图形摘要图形摘要 这种方法意味着将使用两种拮抗性表面活性剂（亲水性表面活性剂和亲脂性表面活性剂）和中间相聚合制成双乳液的配制步骤相结合。双乳液中可聚合物质的插入不应使其不稳定。必须避免一些表现出界面亲和力和干扰复乳液配方的单体。通过改变单体的性质和交联剂与单体的比例，获得了具有高封装效率和各种机械性能的胶囊。图形摘要图形摘要 这种方法意味着将使用两种拮抗性表面活性剂（亲水性表面活性剂和亲脂性表面活性剂）和中间相聚合制成双乳液的配制步骤相结合。双乳液中可聚合物质的插入不应使其不稳定。必须避免一些表现出界面亲和力和干扰复乳液配方的单体。通过改变单体的性质和交联剂与单体的比例，获得了具有高封装效率和各种机械性能的胶囊。图形摘要图形摘要 双乳液中可聚合物质的插入不应使其不稳定。必须避免一些表现出界面亲和力和干扰复乳液配方的单体。通过改变单体的性质和交联剂与单体的比例，获得了具有高封装效率和各种机械性能的胶囊。图形摘要图形摘要 双乳液中可聚合物质的插入不应使其不稳定。必须避免一些表现出界面亲和力和干扰复乳液配方的单体。通过改变单体的性质和交联剂与单体的比例，获得了具有高封装效率和各种机械性能的胶囊。图形摘要图形摘要