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Non-reassuring foetal status and sleep problems in 1-year-old infants in the Japan Environment and Children's Study: a cohort study.
Scientific Reports ( IF 4.6 ) Pub Date : 2020-07-10 , DOI: 10.1038/s41598-020-67856-z
Kazushige Nakahara 1 , Takehiro Michikawa 2 , Seiichi Morokuma 3, 4 , Masanobu Ogawa 4 , Kiyoko Kato 1, 4 , Masafumi Sanefuji 4, 5 , Eiji Shibata 6, 7 , Mayumi Tsuji 6, 8 , Masayuki Shimono 6, 9 , Toshihiro Kawamoto 6 , Shouichi Ohga 5 , Koichi Kusuhara 6, 9 ,
Affiliation  

Abnormal autonomic function may cause false-positive non-reassuring foetal status (fpNRFS) and may also cause sleeping problems after birth. However, an association between fpNRFS and sleeping problems in infants has not been reported. We previously showed an association of NRFS with temperament, including bad mood and frequent crying for long durations in 1-month-old infants. In the present study, we aimed to assess this association in 1-year-old infants. A total of 62,612 single pregnant women were included in the analysis. fpNRFS was identified from medical records. Sleep problems, such as short sleep duration or crying at night, were investigated in 1-year-old infants using a questionnaire for mothers. We used a log-binominal regression model to explore the association of fpNRFS with each sleep problem and to estimate risk ratios (RRs). The number of fpNRFS cases was 2,071, with a frequency of 3.3%. We observed an association of fpNRFS with shorter sleep duration of less than 8 h a night (RR 1.30, 95% confidence intervals [CI] 1.10–1.54), crying at night (RR 1.19, 95% CI 1.03–1.39), and bedtime after 22:00 (RR 1.09, 95% CI 1.00–1.18). fpNRFS may be associated with sleep problems in 1-year-old infants.



中文翻译:

《日本环境与儿童研究:一项队列研究》,对1岁婴儿的令人不安的胎儿状况和睡眠问题进行了研究。

自主神经功能异常可能会导致胎儿假阳性,使人无法安心(fp NRFS),也可能导致出生后出现睡眠问题。但是,尚未报道fp NRFS与婴儿睡眠问题之间的关联。我们以前显示了NRFS与气质的关联,包括1个月大的婴儿的情绪低落和长时间频繁哭泣。在本研究中,我们旨在评估1岁婴儿的这种关联。分析中总共包括62,612名单身孕妇。fpNRFS是从医疗记录中识别出来的。使用母亲问卷调查了1岁婴儿的睡眠问题,例如睡眠时间短或晚上哭泣。我们使用对数二项式回归模型来探索fp NRFS与每个睡眠问题的关联并估计风险比(RRs)。的数量FP NRFS例是2071,与3.3%的频率。我们观察到fp NRFS与较短的睡眠时间少于8夜(RR 1.30,95%置信区间[CI] 1.10–1.54),夜间哭泣(RR 1.19,95%CI 1.03–1.39)和就寝时间有关22:00后(RR 1.09,95%CI 1.00-1.18)。fp NRFS可能与1岁婴儿的睡眠问题有关。

更新日期:2020-07-10
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