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Au nanoparticles modified CuO nanowireelectrode based non-enzymatic glucose detection with improved linearity.
Scientific Reports ( IF 4.6 ) Pub Date : 2020-07-10 , DOI: 10.1038/s41598-020-67986-4
Ashwini Kumar Mishra 1 , Deepak Kumar Jarwal 1 , Bratindranath Mukherjee 2 , Amit Kumar 1 , Smrity Ratan 1 , Manas Ranjan Tripathy 1 , Satyabrata Jit 1
Affiliation  

This paper explores gold nanoparticle (GNP) modified copper oxide nanowires(CuO NWs)based electrode grown on copper foil for non-enzymatic glucose detection in a wide linear ranging up to 31.06 mM, and 44.36 mM at 0.5 M NaOH and 1 M NaOH concentrations. The proposed electrode can be used to detect a very low glucose concentration of 0.3 µM with a high linearity range of 44.36mM and sensitivity of 1591.44 µA mM−1 cm−2. The electrode is fabricated by first synthesizing Cu (OH)2 NWs on a copper foil by chemical etching method and then heat treatment is performed to convert Cu (OH)2 NWs into CuO NWs. The GNPs are deposited on CuO NWs to enhance the effective surface-to-volume ratio of the electrode with improved catalytic activity. The surface morphology has been investigated by XRD, XPS, FE-SEM and HR-TEM analysis. The proposed sensor is expected to detect low-level of glucose in urine, and saliva. At the same time, it can also be used to measure extremely high sugar levels (i.e. hyperglycemia) of ~ 806.5454 mg/dl. The proposed sensor is also capable of detecting glucose after multiple bending of the GNP modified CuO NWs electrode. The proposed device is also used to detect the blood sugar level in human being and it is found that this sensor’s result is highly accurate and reliable.



中文翻译:

Au纳米粒子修饰的基于CuO纳米线电极的非酶葡萄糖检测具有改善的线性度。

本文探索了在铜箔上生长的金纳米粒子(GNP)修饰的氧化铜纳米线(CuO NWs)基电极,用于非酶法葡萄糖检测,线性范围高达31.06 mM,在0.5 M NaOH和1 M NaOH浓度下可达44.36 mM。 。所建议的电极可用于检测0.3 µM的极低葡萄糖浓度,线性范围为44.36mM,灵敏度为1591.44 µA mM -1  cm -2。首先通过化学蚀刻方法在铜箔上合成Cu(OH)2 NW,然后进行热处理以转换Cu(OH)2来制造电极。NW转换为CuO NW。将GNP沉积在CuO NW上,以提高电极的有效表面体积比,同时提高催化活性。通过XRD,XPS,FE-SEM和HR-TEM分析研究了表面形态。该传感器有望检测尿液和唾液中的葡萄糖含量低。同时,它也可用于测量〜806.5454 mg / dl的极高糖水平(即高血糖)。所提出的传感器还能够在GNP修饰的CuO NWs电极多次弯曲后检测葡萄糖。所提出的装置还用于检测人类的血糖水平,并且发现该传感器的结果是高度准确和可靠的。

更新日期:2020-07-10
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