Abstract

A new steroidal alkaloid, michainine (1), was isolated from Fritillaria michailovskyi Fomin, along with nine known compounds 2–10 of different classes, including ribonucleoside, steroids, and fatty acids, which were isolated for the first time from this plant. Their structures were elucidated through extensive spectroscopic techniques, as well as by comparing the data in the literature. Furthermore, the dichloromethane fraction of F. michailovskyi showed a positive butyrylcholinesterase inhibitory activity, along with non-cytotoxicity against 3T3 cell line.

中文翻译：

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一种来自贝母的新甾体生物碱

摘要

从贝母中分离出一种新的甾体生物碱 michainine ( 1 )，以及 9种不同类别的已知化合物2 – 10，包括核糖核苷、类固醇和脂肪酸，这些化合物是首次从该植物中分离出来的。它们的结构是通过广泛的光谱技术以及比较文献中的数据来阐明的。此外，F. michailovskyi的二氯甲烷部分显示出正丁酰胆碱酯酶抑制活性，以及​​对 3T3 细胞系的非细胞毒性。