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Dihydrochalcones from the leaves of Lithocarpus litseifolius
Journal of Asian Natural Products Research ( IF 1.3 ) Pub Date : 2020-07-10 , DOI: 10.1080/10286020.2020.1786067
Wen-Wen Wei 1, 2, 3 , Ping Wu 1 , Xiao-Yin You 1 , Jing-Hua Xue 1 , Liang-Xiong Xu 1 , Xiao-Yi Wei 1
Affiliation  

Abstract

Three new phlorizin derivatives, 6"-O-vanilloylphlorizin (1), 6"-O-(4-hydroxybenzoyl)phlorizin (2), 6"-O-feruloylphlorizin (3), along with four known dihydrochalcones, phlorizin (4), 3-hydroxyphlorizin, trilobatin, and 6"-O-acetylphlorizin were isolated from the leaves of Lithocarpus litseifolius. Their structures were established by analysis of extensive spectroscopic data. The new compounds were shown to be non-cytotoxic when tested against A549, HeLa, HepG2, and MCF-7 cell lines.



中文翻译:

Lithocarpus litseifolius 叶子中的二氢查耳酮

摘要

三种新的根皮苷衍生物,6" -O- vanilloylphlorizin ( 1 ), 6" -O- (4-hydroxybenzoyl)phlorizin ( 2 ), 6" -O- feruloylphlorizin ( 3 ),以及四种已知的二氢查耳酮,根皮苷 ( 4 )从Lithocarpus litseifolius的叶子中分离出3-羟基根皮苷、三叶苷和 6" -O-乙酰根皮苷。它们的结构是通过分析广泛的光谱数据确定的。当针对 A549、HeLa、HepG2 和 MCF-7 细胞系进行测试时,这些新化合物被证明是无细胞毒性的。

更新日期:2020-07-10
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