Present-Day DNA Contamination in Ancient DNA Datasets.,BioEssays

当前位置： X-MOL 学术 › BioEssays › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Present-Day DNA Contamination in Ancient DNA Datasets.
BioEssays ( IF 3.2 ) Pub Date : 2020-07-10 , DOI: 10.1002/bies.202000081
Stéphane Peyrégne ₁ , Kay Prüfer _{1,

2}

Affiliation

Present‐day contamination can lead to false conclusions in ancient DNA studies. A number of methods are available to estimate contamination, which use a variety of signals and are appropriate for different types of data. Here an overview of currently available methods highlighting their strengths and weaknesses is provided, and a classification based on the signals used to estimate contamination is proposed. This overview aims at enabling researchers to choose the most appropriate methods for their dataset. Based on this classification, potential avenues for the further development of methods are discussed.

中文翻译：

古代 DNA 数据集中的现代 DNA 污染。

当今的污染可能导致古代 DNA 研究中的错误结论。有多种方法可用于估计污染，这些方法使用各种信号并适用于不同类型的数据。这里提供了当前可用方法的概述，突出了它们的优点和缺点，并提出了基于用于估计污染的信号的分类。本概述旨在使研究人员能够为其数据集选择最合适的方法。基于这种分类，讨论了进一步开发方法的潜在途径。

更新日期：2020-08-26

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11