当前位置: X-MOL 学术Mater. Today Bio › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Non-covalent protein-based adhesives for transparent substrates-bovine serum albumin vs. recombinant spider silk.
Materials Today Bio ( IF 8.7 ) Pub Date : 2020-07-10 , DOI: 10.1016/j.mtbio.2020.100068
A D Roberts 1, 2 , W Finnigan 1 , P P Kelly 1 , M Faulkner 1 , R Breitling 1 , E Takano 1 , N S Scrutton 1 , J J Blaker 2 , S Hay 1
Affiliation  

Protein-based adhesives could have several advantages over petroleum-derived alternatives, including substantially lower toxicity, smaller environmental footprint, and renewable sourcing. Here, we report that non-covalently crosslinked bovine serum albumin and recombinant spider silk proteins have high adhesive strength on glass (8.53 and 6.28 MPa, respectively) and other transparent substrates. Moreover, the adhesives have high visible transparency and showed no apparent degradation over a period of several months. The mechanism of adhesion was investigated and primarily attributed to dehydration-induced reorganization of protein secondary structure, resulting in the supramolecular association of β-sheets into a densely hydrogen-bonded network.



中文翻译:

非共价蛋白基粘合剂,用于透明底物-牛血清白蛋白与重组蜘蛛丝。

与石油衍生的替代品相比,基于蛋白质的粘合剂可能具有多个优势,包括毒性大大降低,环境足迹更小以及可再生资源。在这里,我们报告非共价交联的牛血清白蛋白和重组蜘蛛丝蛋白在玻璃(分别为8.53和6.28 MPa)和其他透明基质上具有很高的粘合强度。而且,该粘合剂具有高的可见透明性,并且在几个月的时间内没有表现出明显的降解。研究了粘附的机理,其主要归因于脱水诱导的蛋白质二级结构的重组,从而导致β-折叠的超分子缔合成为致密的氢键网络。

更新日期:2020-07-10
down
wechat
bug