当前位置: X-MOL 学术Food Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Preparation of a carboxylated single-walled carbon-nanotube-chitosan functional layer and its application to a molecularly imprinted electrochemical sensor to quantify semicarbazide.
Food Chemistry ( IF 8.5 ) Pub Date : 2020-07-10 , DOI: 10.1016/j.foodchem.2020.127524
Wenlong Yu 1 , Yiwei Tang 1 , Yaxin Sang 1 , Weihua Liu 1 , Shuo Wang 2 , Xianghong Wang 3
Affiliation  

Semicarbazide (SEM) is a protein-bound nitrofurazone metabolite that is detrimental to human health. Therefore, to ensure food safety, it is necessary to detect SEM in food samples. To this end, we developed a novel electrochemical sensor to detect SEM by using a molecularly imprinted polymer (MIP) as the recognition element. Computer-aided molecular modelling was performed to guide the synthesis of the MIP, and subsequently, MIP/carboxylated single-walled carbon-nanotubes/chitosan (MIP/SWNTs-COOH/CS) was prepared as the sensing platform to develop the electrochemical sensor. The linear range of the sensor was 0.04–7.6 ng mL−1, with a detection limit of 0.025 ng mL−1. The sensor was successfully applied to detect SEM in four different real samples, with recoveries ranging from 83.16% to 93.40%. The results indicated that the fabricated electrochemical sensor can be widely applied to detect SEM in the environment and in agri-food products.



中文翻译:

羧化单壁碳纳米管-壳聚糖功能层的制备及其在分子印迹电化学传感器中定量氨基脲的应用。

氨基脲(SEM)是与蛋白质结合的呋喃西林的代谢产物,对人体健康有害。因此,为确保食品安全,有必要对食品样品中的SEM进行检测。为此,我们开发了一种新型的电化学传感器,通过使用分子印迹聚合物(MIP)作为识别元素来检测SEM。进行计算机辅助分子建模以指导MIP的合成,随后,准备MIP /羧化单壁碳纳米管/壳聚糖(MIP / SWNTs-COOH / CS)作为开发电化学传感器的传感平台。传感器的线性范围为0.04–7.6 ng mL -1,检测极限为0.025 ng mL -1。该传感器成功地用于检测四种不同真实样品中的SEM,回收率从83.16%到93.40%。结果表明,所制备的电化学传感器可广泛应用于环境和农产品中的SEM检测。

更新日期:2020-07-14
down
wechat
bug