Gauze is the leading dressing for wound management. However, infection and tissue adhesion pose serious challenges to the application of gauzes. Herein, inspired by the self-cleaning property of lotus leaf, we develop a novel antiadhesive and antibacterial gauze. The gauze, named Lotus@Gauze, is fabricated by decorating an ordinary medical gauze sequentially with polydopamine, perfluorocarbon and silver nanoparticle to obtain a lotus leaf-mimic surface structure. Lotus@Gauze exhibits excellent antiadhesive and antibacterial effects, and its antibacterial ability is enhanced under NIR irradiation due to the photothermal effect of polydopamine. Furthermore, in vivo results reveal that, in comparison with clinically available antiadhesive or antibacterial gauzes, Lotus@Gauze shows better efficacy in promoting infectious wound regeneration due to its low tissue adhesion and effective bactericidal activity. Overall, this study explores a new attempt to overcome the challenge of tissue adhesion and infection by integrating antiadhesive and antibacterial properties into one piece of simple gauze.

纱布是伤口处理的主要敷料。然而，感染和组织粘附对纱布的使用提出了严重的挑战。在此，受荷叶的自洁特性启发，我们开发了一种新型的抗粘和抗菌纱布。该纱布名为Lotus @ Gauze，是通过依次用聚多巴胺，全氟化碳和银纳米粒子装饰普通医用纱布而制成的，从而获得模仿荷叶的表面结构。Lotus @ Gauze具有出色的抗粘连和抗菌作用，并且由于聚多巴胺的光热作用，其在NIR照射下的抗菌能力得到增强。此外，体内结果表明，与临床上可用的抗粘剂或抗菌纱布相比，Lotus @ Gauze由于其组织粘附力低和有效的杀菌活性，在促进感染性伤口再生方面显示出更好的功效。总的来说，这项研究探索了通过将抗粘连和抗菌性能整合到一块简单的纱布中来克服组织粘连和感染挑战的新尝试。