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Image quality of list-mode proton imaging without front trackers
Physics in Medicine & Biology ( IF 3.5 ) Pub Date : 2020-07-08 , DOI: 10.1088/1361-6560/ab8ddb
Jarle Rambo Slie 1, 2, 3 , Lennart Volz 3, 4, 5 , Helge Egil Seime Pettersen 6 , Pierluigi Piersimoni 2 , Odd Harald Odland 2, 6 , Dieter Rhrich 2 , Hvard Helstrup 1 , Thomas Peitzmann 7 , Kjetil Ullaland 2 , Monika Varga-Kofarago 8 , Shruti Mehendale 2 , Ola Slettevoll Grttvik 2 , Viljar Nilsen Eikeland 2 , Ilker Meric 1, 9 , Joao Seco 4, 5, 9
Affiliation  

List mode proton imaging relies on accurate reconstruction of the proton most likely path (MLP) through the patient. This typically requires two sets of position sensitive detector systems, one upstream (front) and one downstream (rear) of the patient. However, for a clinical implementation it can be preferable to omit the front trackers (single-sided proton imaging). For such a system, the MLP can be computed from information available through the beam delivery system and the remaining rear tracker set. In this work, we use Monte Carlo simulations to compare a conventional double-sided (using both front and rear detector systems) with a single-sided system (only rear detector system) by evaluating the spatial resolution of proton radiographs (pRad) and proton CT images (pCT) acquired with these set-ups. Both the pencil beam spot size, as well as the spacing between spots was also adjusted to identify the impact of these beam parameters on the image quality. Relying only ...

中文翻译:

没有前置跟踪器的列表模式质子成像的图像质量

列表模式质子成像依赖于通过患者的质子最可能路径(MLP)的准确重建。这通常需要两组位置敏感检测器系统,即患者的上游(前)和下游(后)一组。但是,对于临床实施而言,最好省略前跟踪器(单面质子成像)。对于这样的系统,可以从通过光束传输系统和其余的后跟踪器组获得的信息中计算出MLP。在这项工作中,我们通过评估质子射线照片(pRad)和质子的空间分辨率,使用蒙特卡罗模拟将传统的双面系统(使用前后探测器系统)与单面系统(仅使用后探测器系统)进行比较。通过这些设置获取的CT图像(pCT)。铅笔束光斑大小 还调整了光点之间的间距,以识别这些光束参数对图像质量的影响。仅依靠...
更新日期:2020-07-09
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