Near Full-Length Genomic Characterization of a Novel HIV-1 Circulating Recombinant Form (CRF106_cpx) Identified Among Heterosexuals in China.,AIDS Research and Human Retroviruses

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Near Full-Length Genomic Characterization of a Novel HIV-1 Circulating Recombinant Form (CRF106_cpx) Identified Among Heterosexuals in China.
AIDS Research and Human Retroviruses ( IF 1.5 ) Pub Date : 2020-10-05 , DOI: 10.1089/aid.2020.0101
Jiajia Zhou ₁ , Miaomiao Li ₁ , Chen Min ₂ , Yanling Ma ₁ , Yiming Shao ₁ , Hui Xing ₁

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In our study, we reported a novel CRF01_AE/B/C human immunodeficiency virus type 1 (HIV-1) recombinant form among six epidemiologically unlinked heterosexual patients in Yunnan, China. It was named CRF106_cpx (this is temporary as we have not received the circulating recombinant form [CRF] number from HIV databases). After sequencing and analyzing of the near full-length genome, we found that CRF106_cpx was generated by three B segments and two CRF01_AE segments inserted into the C backbone. There was quite a bit of diversity between sequences of CRF106_cpx, so this seems to be a CRF that has been spreading for many years.

更新日期：2020-10-07

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