Myocardial Steatosis Among Antiretroviral Therapy-Treated People With Human Immunodeficiency Virus Participating in the REPRIEVE Trial.,The Journal of Infectious Diseases

当前位置： X-MOL 学术 › J. Infect. Dis. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Myocardial Steatosis Among Antiretroviral Therapy-Treated People With Human Immunodeficiency Virus Participating in the REPRIEVE Trial.
The Journal of Infectious Diseases ( IF 6.4 ) Pub Date : 2020-07-09 , DOI: 10.1093/infdis/jiaa245
Tomas G Neilan ₁ , Kim-Lien Nguyen ₂ , Vlad G Zaha ₃ , Kara W Chew ₄ , Leavitt Morrison ₅ , Ntobeko A B Ntusi ₆ , Mabel Toribio ₇ , Magid Awadalla ₁ , Zsofia D Drobni ₁ , Michael D Nelson ₈ , Tricia H Burdo ₉ , Marije Van Schalkwyk ₁₀ , Paul E Sax ₁₁ , Daniel J Skiest ₁₂ , Karen Tashima ₁₃ , Raphael J Landovitz ₁₄ , Eric Daar ₁₅ , Alysse G Wurcel ₁₆ , Gregory K Robbins ₁₇ , Robert K Bolan ₁₈ , Kathleen V Fitch ₇ , Judith S Currier ₄ , Gerald S Bloomfield ₁₉ , Patrice Desvigne-Nickens ₂₀ , Pamela S Douglas ₂₁ , Udo Hoffmann ₁ , Steven K Grinspoon ₇ , Heather Ribaudo ₅ , Rodney Dawson ₂₂ , Matthew Bidwell Goetz ₂₃ , Mamta K Jain ₂₄ , Alberta Warner ₂ , Lidia S Szczepaniak ₂₅ , Markella V Zanni ₇

Affiliation

Cardiovascular Imaging Research Center, Department of Radiology and Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Division of Cardiology, David Geffen School of Medicine at the University of California, Los Angeles and the Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California, USA.
Division of Cardiovascular Medicine, Department of Medicine, Advanced Imaging Research Center, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, California, USA.
Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
Division of Cardiology, Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Applied Physiology and Advanced Imaging Laboratory, Department of Kinesiology, University of Texas at Arlington, Arlington, Texas, USA.
Department of Neuroscience, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Family Clinical Research Unit, Division of Adult Infectious Diseases, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.
Division of Infectious Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Department of Medicine, University of Massachusetts Medical School-Baystate, Springfield, Massachusetts, USA.
Division of Infectious Diseases, The Miriam Hospital and Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Center for Clinical AIDS Research and Education, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, California, USA.
Lundquist Institute at Harbor-University of California, Los Angeles Medical Center and David Geffen School of Medicine at the University of Los Angeles, Los Angeles, California, USA.
Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, USA.
Division of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Los Angeles Lesbian Gay Bisexual Transgender Center, Los Angeles, California, USA.
Duke Clinical Research Institute, Duke Global Health Institute, Department of Medicine, Duke University, Durham, North Carolina, USA.
National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Division of Pulmonology and Department of Medicine, University of Cape Town Lung Institute, Mowbray, Cape Town, South Africa.
Infectious Diseases Section, Department of Medicine, Veterans Affairs Greater Los Angeles Healthcare System and David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, California, USA.
Division of Infectious Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Biomedical Research Consulting in Magnetic Resonance Spectroscopy, Albuquerque, New Mexico, USA.

People with human immunodeficiency virus (PWH) face increased risks for heart failure and adverse heart failure outcomes. Myocardial steatosis predisposes to diastolic dysfunction, a heart failure precursor. We aimed to characterize myocardial steatosis and associated potential risk factors among a subset of the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) participants.

中文翻译：

参加 REPRIEVE 试验的抗逆转录病毒疗法治疗的人类免疫缺陷病毒患者的心肌脂肪变性。

人类免疫缺陷病毒 (PWH) 患者面临更高的心力衰竭风险和心力衰竭不良后果。心肌脂肪变性易导致舒张功能障碍，这是心力衰竭的先兆。我们的目的是在预防 HIV 血管事件随机试验 (REPRIEVE) 参与者的子集中描述心肌脂肪变性和相关潜在危险因素的特征。

更新日期：2020-07-09

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文

全部期刊列表>>