Holey g-C₃N₄ (H-C₃N₄) with in situ grown Au nanoparticles (Au@H-C₃N₄) was synthesized to produce high performance and ultrasensitive SERS active substrates. The H-C₃N₄ with the porous structure provided the support for embedding enough Au NPs, which avoided the aggregation of Au NPs on the surface of H-C₃N₄. The results showed that crystal violet as a Raman probe showed a detection level of 2.7 × 10⁻⁹ M with an enhancement factor of 6.8 × 10⁵. Au@H-C₃N₄ was used successfully to detect the residues of prohibited additives, melamine and sodium thiocyanate, from milk samples, which displayed a good linear range from 1 × 10⁻⁴ to 5 × 10⁻⁷ M (R² = 0.986) and 1 × 10⁻³ to 5 × 10⁻⁶ M (R² = 0.971), respectively. In this study, Au@H-C₃N₄ SERS substrates with high sensitivity have high potential as SERS platform for trace detection.

合成了具有原位生长的Au纳米粒子（Au @ HC ₃ N ₄）的有孔gC ₃ N ₄（HC ₃ N ₄），以生产高性能和超灵敏的SERS活性基质。具有多孔结构的HC ₃ N ₄为嵌入足够的Au NPs提供了支撑，避免了Au NPs在HC ₃ N ₄表面上的聚集。结果显示，作为拉曼探针的结晶紫显示检测水平为2.7×10 ^-9 M，增强因子为6.8×10 ⁵。金@HC ₃ N ₄被成功地用于检测违禁添加剂，三聚氰胺和硫氰酸钠的残基，从牛奶样品，其显示了良好的线性范围为1×10 ^-4至5×10 ^-7 M（ - [R ² = 0.986）和1×10 ^{- 3}至5×10 ^-6 M（R ² = 0.971）。在这项研究中，具有高灵敏度的Au @ HC ₃ N ₄ SERS底物作为痕量检测的SERS平台具有很高的潜力。