Objective The study was done to investigate the role of susceptibility-weighted imaging (SWI) in characterization of cerebral microbleeds (CMBs) and incidence of CMBs in acute ischemic stroke obese patients. Materials and methods We recruited 120 acute ischemic stroke obese patients. All participants or their relatives gave written informed consent. MRI of the brain with SWI sequences was done for all patients. Results SWI showed 30% of the patients have CMBs. The total numbers of CMBs were statistically significant higher in small vessel diseases (SVDs) than large vessel diseases (LVDs) ( P = 0.008). According to the severity scale, CMBs were more prominent in patients with grade 0 (70%) followed by grade III (25.8%) then grade II (4.2%). BMI was independent risk factors for developing CMBs as shown in simple regression analysis ( х 2 = 6.008, P = 0.002). SVDs and hypertension were statistically significant independent predictors and had higher odds to exhibit CMBs. Patients with SVDs had 5.3 times higher odds to exhibit CMBs ( P = 0.002) while patients with hypertension had 3.9 times higher odds to exhibit CMBs ( P = 0.032). Conclusion SWI is a gold standard MR imaging technique in diagnosis and characterization of CMBs with more prevalence especially in obese patients suffering from acute ischemia stroke due to SVDs. Hypertension was an independent risk factor for development of CMBs but IHD, use of antiplatelet medications, increased BMI, and dyslipidemia must be taken into consideration.

中文翻译：

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磁化率加权成像在急性缺血性卒中埃及肥胖患者脑微出血特征中的作用

目的 本研究旨在探讨磁敏感加权成像 (SWI) 在急性缺血性卒中肥胖患者脑微出血 (CMB) 特征和 CMB 发生率中的作用。材料和方法 我们招募了 120 名急性缺血性卒中肥胖患者。所有参与者或其亲属都签署了书面知情同意书。对所有患者进行了具有 SWI 序列的大脑 MRI。结果 SWI显示30%的患者有CMBs。小血管疾病 (SVD) 中 CMB 的总数在统计学上显着高于大血管疾病 (LVD) ( P = 0.008)。根据严重程度等级，CMB 在 0 级 (70%) 患者中更为突出，其次是 III 级 (25.8%) 然后是 II 级 (4.2%)。如简单回归分析所示，BMI 是发展 CMB 的独立危险因素 (х 2 = 6.008, P = 0.002）。SVD 和高血压是具有统计学意义的独立预测因子，并且表现出 CMB 的几率更高。SVD 患者出现 CMB 的几率高 5.3 倍（ P = 0.002），而高血压患者出现 CMB 的几率高 3.9 倍（ P = 0.032）。结论 SWI 是诊断和表征 CMB 的金标准 MR 成像技术，尤其在 SVD 引起的急性缺血性卒中的肥胖患者中更普遍。高血压是 CMB 发生的独立危险因素，但必须考虑 IHD、抗血小板药物的使用、BMI 增加和血脂异常。002) 而高血压患者出现 CMB 的几率高 3.9 倍 ( P = 0.032)。结论 SWI 是诊断和表征 CMB 的金标准 MR 成像技术，尤其在 SVD 引起的急性缺血性卒中的肥胖患者中更普遍。高血压是 CMB 发生的独立危险因素，但必须考虑 IHD、抗血小板药物的使用、BMI 增加和血脂异常。002) 而高血压患者出现 CMB 的几率高 3.9 倍 ( P = 0.032)。结论 SWI 是诊断和表征 CMB 的金标准 MR 成像技术，尤其在 SVD 引起的急性缺血性卒中的肥胖患者中更普遍。高血压是 CMB 发生的独立危险因素，但必须考虑 IHD、抗血小板药物的使用、BMI 增加和血脂异常。