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Open Space Diffusive Filter for Simultaneous Species Retrieval and Separation.
Analytical Chemistry ( IF 6.7 ) Pub Date : 2020-07-08 , DOI: 10.1021/acs.analchem.0c02176
Prerit Mathur 1, 2 , Anna Fomitcheva Khartchenko 1, 2 , Andrew J deMello 2 , Govind V Kaigala 1
Affiliation  

We present a novel method for the local retrieval of surface bound species and their rapid in-line separation using an open space microfluidic device. Separation can be performed in less than 30 s using the difference in diffusivities within parallel microfluidic flows. As a proof-of-principle, we report the rapid and efficient filtration of polystyrene beads from small molecules and surface bound red blood cells from dimethyl sulfoxide for antigen typing.

中文翻译:

同时进行物种检索和分离的开放空间扩散过滤器。

我们提出了一种新的方法来对表面结合的物种进行本地检索,并使用开放空间微流体装置对其进行快速在线分离。利用平行微流体流中的扩散率差异,可以在不到30 s的时间内完成分离。作为原理的证明,我们报道了小分子聚苯乙烯珠的快速有效过滤和二甲基亚砜中表面结合红细胞的快速过滤,用于抗原分型。
更新日期:2020-09-01
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