Secretory proteins undergo multiple rounds of co- and post-translational quality control checks inside the cell, but how their integrity is maintained outside the cell is an emerging topic. A study establishes a model system to investigate how the extracellular proteome is protected and integrates its findings into existing immune pathways.

中文翻译：

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由外而内的蛋白质稳态。

分泌蛋白在细胞内经过多轮共翻译和翻译后质量控制检查，但如何在细胞外保持其完整性是一个新兴话题。一项研究建立了一个模型系统来研究如何保护细胞外蛋白质组并将其发现整合到现有的免疫途径中。