Three dimensional (3D) crumpling of two dimensional (2D) materials provides new opportunities to modulate mechanical, optical, surface, and chemical properties. However, investigation of the effect of 3D crumpling on 2D material liquid interaction has been limited. In this perspective, we will review crumple/texture induced heterogeneous surface properties including chemical modification, energy corrugation, and electronic structure perturbation which may modulate fluid interaction. We will then describe simulations of fluid interaction in systems resembling 3D textured 2D materials, principally nanotubes, which have begun to substantiate perturbations to fluid structure driven by texture induced modification of the 2D material surface. Furthermore, we will detail current experimental understanding of how texture induced modulation of interactions with pure solvent affect macroscale wetting characteristics including textured driven transitions in water contact from Wentzel to Cassie Baxter states. Following this discussion of how texturing affects the interaction of 2D materials with pure solvent, we will detail cutting edge explorations of how texturing modifies interaction with ions and other chemical species dispersed in solvent phases. Particular focus will be placed on recent simulations of aqueous phase molecular interaction with crumpled 2D materials which show that crumpling increases the thickness of the electrical double layer (EDL) formed near a 2D material surface. This increased EDL thickness has allowed for the development of biomolecule sensors with gigantic sensitivity and the monitoring and templating of cells including neurons and myotubes. Sill, considerable work is needed to elucidate the effect of different crumpling geometries on the local properties of the full range of 2D materials, how these variation in local properties perturb fluid structure and molecular interaction, and how these tuned interactions enable diverse opportunities such as sensing, energy storage, and control of biological interaction.

二维（2D）材料的三维（3D）压皱为调制机械，光学，表面和化学性质提供了新的机会。但是，对3D压皱对2D材料液体相互作用的影响的研究受到限制。从这个角度来看，我们将回顾由压皱/纹理引起的异质表面特性，包括化学修饰，能量波纹和可能调节流体相互作用的电子结构扰动。然后，我们将描述类似于3D纹理2D材料（主要是纳米管）的系统中流体相互作用的模拟，该系统已开始证实对2D材料表面的纹理诱导改性驱动的流体结构的扰动。此外，我们将详细说明关于由纹理引起的与纯溶剂相互作用的调制如何影响宏观润湿特性的当前实验性理解，包括从Wentzel到Cassie Baxter态水接触中的纹理驱动跃迁。在讨论了纹理化如何影响2D材料与纯溶剂之间的相互作用之后，我们将详细探讨纹理化如何改变与分散在溶剂相中的离子和其他化学物质之间的相互作用。将特别关注与皱纹2D材料的水相分子相互作用的最新模拟，这表明皱纹增加了在2D材料表面附近形成的双电层（EDL）的厚度。EDL厚度的增加允许开发具有巨大灵敏度的生物分子传感器，并可以监视和模板化包括神经元和肌管的细胞。仍然需要大量工作来阐明不同皱缩几何形状对整个2D材料局部特性的影响，局部特性的这些变化如何扰动流体结构和分子相互作用以及这些调整后的相互作用如何为诸如传感等多种机会提供机会，能量存储和生物相互作用的控制。