In this issue of Cell Host & Microbe, Bruggisser et al. show that Clostridium perfringens β-toxin (CPB) binds platelet endothelial cell adhesion molecule-1 (PECAM-1) (also known as CD31) to induce membrane pores. The discovery explains the cell type specificity for CPB and, in large part, the basic pathophysiology of disease.

中文翻译：

---

一切照亮的产气荚膜梭菌β毒素。

在本期《细胞宿主与微生物》中，布鲁吉瑟尔等人。表明产气荚膜梭菌β毒素（CPB）与血小板内皮细胞粘附分子1（PECAM-1）（也称为CD31）结合以诱导膜孔。该发现解释了CPB的细胞类型特异性，并在很大程度上解释了疾病的基本病理生理。