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A Blood Bank Network Design Problem with Integrated Facility Location, Inventory and Routing Decisions
Networks and Spatial Economics ( IF 1.6 ) Pub Date : 2020-07-07 , DOI: 10.1007/s11067-020-09500-x
Onur Kaya , Dogus Ozkok

We aim to design an effective supply chain network for a blood distribution system to satisfy the needs of hospitals in a certain region. In the analyzed current system, each hospital keeps a certain level of inventory, received at certain time periods by the shipments from a main blood bank. We propose an alternative system, in which some of the hospitals are selected as local blood banks (LBB) and all other hospitals will be assigned to an LBB. More frequent shipments will be made from LBBs to these hospitals, leading to lower inventory levels to be kept at each hospital. The inventories kept separately at the hospitals in the current system will be pooled at the selected LBBs in the proposed system. We develop a mixed integer nonlinear programming (MINLP) model to determine the optimal selection of LBBs, assignment of hospitals to LBBs, optimal inventory levels at each LBB and routing decisions among the facilities in order to minimize total system costs. We also propose a piecewise linear approximation method and a simulated annealing heuristic approach to find the solution of this problem. The proposed model and the solution techniques are applied on a real life case study for the blood distribution network in Istanbul. It is observed that significant improvements can be obtained by the proposed system when compared to the current design. Performances of the solution methods are also compared and a sensitivity analysis related to system parameters is presented via detailed numerical experiments.

中文翻译:

综合设施位置,库存和路线决策的血库网络设计问题

我们旨在为血液分配系统设计有效的供应链网络,以满足特定地区医院的需求。在当前分析的系统中,每家医院都保持一定水平的库存,这些库存在特定时间段内由主要血库的货物接收。我们提出了一种替代系统,其中一些医院被选为当地血库(LBB),而所有其他医院将被分配到LBB。从LBB到这些医院的运送将更加频繁,从而降低了每家医院的库存水平。在当前系统中,分别存放在医院中的库存将在建议系统中的选定LBB处汇总。我们开发了混合整数非线性规划(MINLP)模型来确定LBB的最佳选择,将医院分配给LBB,每个LBB的最佳库存水平和设施之间的路由决策,以最大程度地降低系统总成本。我们还提出了一种分段线性逼近方法和一种模拟退火启发式方法来找到该问题的解决方案。所提出的模型和求解技术被应用于伊斯坦布尔血液分配网络的实际案例研究。可以看出,与当前设计相比,所提出的系统可以获得明显的改进。还比较了求解方法的性能,并通过详细的数值实验进行了与系统参数有关的灵敏度分析。我们还提出了一种分段线性逼近方法和一种模拟退火启发式方法来找到该问题的解决方案。所提出的模型和求解技术被应用于伊斯坦布尔血液分配网络的实际案例研究。可以看出,与当前设计相比,所提出的系统可以获得明显的改进。还比较了求解方法的性能,并通过详细的数值实验对与系统参数有关的灵敏度进行了分析。我们还提出了一种分段线性逼近方法和一种模拟退火启发式方法来找到该问题的解决方案。所提出的模型和求解技术被应用于伊斯坦布尔血液分配网络的实际案例研究。可以看出,与当前设计相比,所提出的系统可以获得明显的改进。还比较了求解方法的性能,并通过详细的数值实验进行了与系统参数有关的灵敏度分析。可以看出,与当前设计相比,所提出的系统可以获得明显的改进。还比较了求解方法的性能,并通过详细的数值实验对与系统参数有关的灵敏度进行了分析。可以看出,与当前设计相比,所提出的系统可以获得明显的改进。还比较了求解方法的性能,并通过详细的数值实验进行了与系统参数有关的灵敏度分析。
更新日期:2020-07-07
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