Abstract

New derivatives of chromeno[4,3-b]quinolin-6-one were synthesized using novel SO₃H-tryptamine supported on Fe₃O₄@SiO₂@CPS which could be recycled as an effective magnetic nanocatalyst. SEM, EDX, XRD, FT-IR, TGA, VSM and BET analyses were utilized to confirm the magnetic nanocatalyst structure. Evaluation of Antimicrobial (antibacterial and antifungal) function of magnetic nanocatalyst as well as derivatives undergone synthesis was carried out according to MIC, MBC and MFC values. Moreover, evaluation of the derivatives subject to synthesis was performed according to DPPH free radical besides the biological features, in order to obtain justifiable biological features.

Graphic abstract

中文翻译：

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Fe 3 O 4 @SiO 2 @CPS负载的SO 3 H-色胺为可循环利用和生物活性磁性纳米催化剂的合成和评价新型铬诺[4,3-b]喹啉-6-酮衍生物的生物活性

摘要

利用Fe ₃ O ₄ @SiO ₂ @CPS负载的新型SO ₃ H-色胺，合成了铬诺[4,3-b]喹啉-6-的新衍生物，该衍生物可作为有效的磁性纳米催化剂回收利用。SEM，EDX，XRD，FT-IR，TGA，VSM和BET分析被用于确认磁性纳米催化剂的结构。根据MIC，MBC和MFC值评估磁性纳米催化剂及其合成衍生物的抗菌（抗菌和抗真菌）功能。此外，除了生物学特征之外，还根据DPPH自由基对要合成的衍生物进行评估，以获得合理的生物学特征。

图形摘要