Affordable, noninvasive methods of predicting functional decline are needed for individuals at risk for Alzheimer’s disease. This study tested whether a timed upper-extremity motor task predicted functional decline over one year in 79 adults diagnosed with amnestic mild cognitive impairment. Participants completed subjective and objective measures of daily functioning at baseline and one year later. Motor task performance and delayed memory were also evaluated at baseline. Motor task performance was a significant predictor of one-year follow-up daily functioning, improving model fits by 18– 35%. Thus, motor behavior has potential to be an affordable enrichment strategy that is sensitive to functional decline.

中文翻译：

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使用定时运动任务来预测遗忘性轻度认知障碍的一年功能衰退。

对于有患阿尔茨海默病风险的个体，需要经济实惠的非侵入性方法来预测功能衰退。这项研究测试了 79 名被诊断患有遗忘型轻度认知障碍的成年人，一项定时上肢运动任务是否能预测一年后的功能衰退。参与者在基线和一年后完成了日常功能的主观和客观测量。运动任务表现和延迟记忆也在基线进行了评估。运动任务表现是一年随访日常功能的重要预测指标，将模型拟合提高了 18-35%。因此，运动行为有可能成为一种对功能衰退敏感的负担得起的丰富策略。