INTRODUCTION: Cushings disease is a condition of hypercortisolaemia caused by a functional adrenocorticotropic hormone secreting pituitary adenoma. Surgical management is the first line of treatment for Cushings disease, but remains challenging in some cases. Various imaging modalities have been tried in an attempt to improve surgical remission rates. However, the sizes and certainties of any effect, in comparison to standard preoperative MRI imaging, remain unclear. METHODS: This protocol has been developed according to the PRISMA-P 2015 standards. Searches of PubMed and Embase were conducted on 21 May 2020, and abstract screening commenced. The eligibility criteria, items for data extraction, and the analysis plan are laid out in this protocol, and uploaded prior to commencement of formal data extraction. DISCUSSION: The results of this review will inform decision-making and priority-setting at the clinical, organisational and research levels. The results will be disseminated throughout the international neurosurgical community through presentations and publications.

中文翻译：

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先进的成像技术可改善接受经蝶窦手术治疗的库欣病患者的缓解率：系统评价和荟萃分析的方案

简介：库欣病是由分泌促肾上腺皮质激素的垂体腺瘤引起的皮质醇过多症。手术管理是库欣病的第一线治疗方法，但在某些情况下仍然具有挑战性。为了提高手术缓解率，已经尝试了各种成像方式。但是，与标准术前MRI成像相比，任何效果的大小和确定性仍不清楚。方法：该协议是根据PRISMA-P 2015标准开发的。2020年5月21日对PubMed和Embase进行了搜索，并开始了摘要筛选。在该协议中列出了资格标准，数据提取项目和分析计划，并在开始正式数据提取之前将其上载。讨论：审查的结果将为临床，组织和研究水平的决策和优先事项提供信息。结果将通过演讲和出版物在整个国际神经外科界传播。