Corticobasal syndrome (CBS) is characterized by unilateral atrophy of the brain. New diagnostic criteria for CBS include intermediate somatosensory dysfunction. Here, we aimed to carefully examine intermediate somatosensory function to identify tests which can assess impairment in CBS patients. Using voxel-based morphometry (VBM), we also aimed to show the anatomical bases of these impairments. Subjects included 14 patients diagnosed with CBS and 14 patients with Parkinson's disease (PD). Patients were evaluated using intermediate somatosensory tests and neuropsychological assessments. VBM was used to analyze differences in gray matter volumes between CBS and PD patients. In the PD group, no tests showed a significant difference between the dominant-side onset and the non-dominant-side onset. In the CBS group, all tests showed worse scores on the affected side. For detecting intermediate somatosensory dysfunction in CBS, two tests are recommended: tactile object naming and 2-point discrimination. VBM analysis showed that the volume of the left post- and pre-central gyrus, and both sides of the supplementary motor area were significantly decreased in the CBS group compared to the PD group. Although CBS remains untreatable, early and correct diagnosis is possible by performing close examination of intermediate somatosensory function.

皮质基底动脉综合症（CBS）的特征在于大脑的单侧萎缩。CBS的新诊断标准包括中度体感功能障碍。在这里，我们的目的是仔细检查中间的身体感觉功能，以鉴定可以评估CBS患者损伤的测试。使用基于体素的形态计量学（VBM），我们还旨在显示这些损伤的解剖学基础。受试者包括14位被诊断患有CBS的患者和14位患有帕金森病（PD）的患者。使用中间体感测试和神经心理学评估对患者进行评估。VBM用于分析CBS和PD患者之间灰质体积的差异。在PD组中，没有测试显示显性侧发作与非显性侧发作之间有显着差异。在CBS组中，所有测试均显示患侧得分较差。为了检测CBS中的中间体感功能障碍，建议进行两项测试：触觉对象命名和2点识别。VBM分析显示，与PD组相比，CBS组的左后中央和前中央回的体积以及辅助运动区的两侧均明显减少。尽管CBS仍然无法治疗，但通过对中间的体感功能进行仔细检查，可以进行早期正确的诊断。与PD组相比，CBS组的辅助运动区两侧均明显减少。尽管CBS仍无法治疗，但通过仔细检查中间的体感功能可以早期而正确的诊断。与PD组相比，CBS组的辅助运动区两侧明显减少。尽管CBS仍无法治疗，但通过仔细检查中间的体感功能可以早期而正确的诊断。