Shade et al. demonstrate that people with peanut allergies produce IgE antibodies that are enriched for sialic acid‐containing glycoforms. The sialylated IgE triggered significantly more degranulation by basophils and mast cells, suggesting intrinsic functional differences between IgEs from allergic and nonallergic subjects.

中文翻译：

---

免疫球蛋白E唾液酸化调节过敏反应。

阴影等。证明对花生过敏的人产生的IgE抗体富含唾液酸糖型。唾液酸化的IgE触发了更多的嗜碱性粒细胞和肥大细胞脱颗粒，这表明来自过敏和非过敏受试者的IgE之间固有的功能差异。