Sennoside A (dianthrone glycoside) shows laxative properties and used as a folk traditional medicine. Sennoside A capped silver nanoparticles (Ag/sennoside A) were synthesized at room temperature for the first time by using sennoside A as reducing and capping agent. UV–visible spectroscopic data reveals that the absorption peaks of pure sennoside A was appeared at 266, and 340 nm, which red shifted to 304, and 354 nm at higher sennoside A concentration. Upon addition of the Ag⁺ ions, an additional peak also observed at 398 nm, indicating the formation of spherical sennoside A capped silver nanoparticles (Ag/sennoside A). Cetyltrimethylammonium bromide (CTAB) was used a stabilizing agent to determine the role of cationic micelles on the nucleation and growth processes of Ag/sennoside A NPs formation. The 2,2-diphenyl-1-picrylhydrazyl nitrogen radical (DPPH^·), two bacteria strains (Staphylococcus aureus and Escherichia coli) and two yeast strains (Candida albicans ATCC 10231 and Candida parapsilosis ATCC 22019) were used to determine the antioxidant and antimicrobial properties of Ag/sennoside A NPs. In addition, Rhein-9-anthrone (4,5-dihydroxy-10-oxo-9H-anthracene-2-carboxylate) was isolated from the acidic hydrolysis of glycoside linkage of sennoside A and characterized. The antioxidant and antimicrobial activities of rhein-9-anthrone were also determined against DPPH radical, antibacterial and antifungal strains. The minimum inhibitory concentration was determined and discussed.

Sennoside A（二蒽酮糖苷）具有泻药特性，用作民间传统药物。以番泻苷A为还原剂和封端剂，首次在室温下合成了番泻苷A封端银纳米颗粒（Ag/sennoside A）。紫外-可见光谱数据显示纯番泻苷A的吸收峰出现在266和340 nm处，当番泻苷A浓度较高时，吸收峰红移至304和354 nm。添加 Ag ⁺离子后，还在 398 nm 处观察到另一个峰，表明形成了球形番泻苷 A 封端的银纳米颗粒（Ag/番泻苷 A）。使用十六烷基三甲基溴化铵 (CTAB) 作为稳定剂来确定阳离子胶束对 Ag/番泻苷 A 纳米颗粒形成的成核和生长过程的作用。采用2,2-二苯基-1-三硝基苯肼基氮自由基(DPPH ^· )、两种细菌菌株(金黄色葡萄球菌和大肠杆菌)和两种酵母菌株(白色念珠菌ATCC 10231和近平滑念珠菌ATCC 22019)测定其抗氧化和抗菌活性。 Ag/番泻苷 A NP 的特性。此外，从番泻苷A糖苷键的酸性水解中分离出大黄酸-9-蒽酮（4,5-二羟基-10-氧代-9H-蒽-2-羧酸酯）并进行了表征。还测定了大黄酸 9-蒽酮对 DPPH 自由基、抗菌和抗真菌菌株的抗氧化和抗菌活性。确定并讨论了最低抑制浓度。