Magnetic core-shell Fe₂O₃@polymer-Pd/Cu nanocomposites (NCs) were developed as efficient and sustainable nanocatalysts for cross-coupling reactions. The designed NCs consisted of three components: i) a magnetic core (Fe₂O₃ nanoparticle), which allowed the recovery and reuse of the NCs, enhancing thus their attractiveness as green catalysts; ii) a catechol-based polymer coating, chosen because of its strong chelating ability towards metal ions, and its potential to be obtained from biomass (lignin depolymerization); and iii) catalytically active metal nanoparticles (Pd and Cu NPs) immobilized via in situ formation onto the polymeric shell. As-prepared Pd-based NCs successfully catalyzed Suzuki-Miyaura cross-coupling reactions, achieving yields between 87% and 97% in only 20–40 min depending on the aryl halides and boronic acid derivatives. Similarly, Cu-based NCs exhibited a quite good catalytic efficiency (> 80%) in the synthesis of propargylamines via A³ coupling reaction of phenylacetylene with various aldehydes and amines. Importantly, these NCs presented a good reusability, without significant decrease in efficiency after several cycles. However, the major advantage of the designed NCs is the lower Pd or Cu content (1.5 wt% and 2.6 wt%, respectively) as compared to most of the reported similar catalysts (between 3 – 6 wt% for Pd and > 5 wt% for Cu), which is a key challenge in view of developing cost-effective and environment-friendly catalysts while maintaining a high efficiency.

磁性核-壳Fe ₂ O ₃ @聚合物-Pd / Cu纳米复合材料（NCs）被开发为交叉偶联反应的有效和可持续的纳米催化剂。设计的NCs包含三个成分：i）磁芯（Fe ₂ O ₃纳米颗粒），可以回收和再利用NCs，从而增强其作为绿色催化剂的吸引力；ii）选择一种基于邻苯二酚的聚合物涂层，因为它对金属离子具有很强的螯合能力，并且具有从生物质中获得的潜力（木质素解聚）；iii）通过原位固定的催化活性金属纳米颗粒（Pd和Cu NPs）形成到聚合物壳上。制备好的基于Pd的NCs成功催化了Suzuki-Miyaura交叉偶联反应，仅20到40分钟即可达到87％至97％的产率，具体取决于芳基卤化物和硼酸衍生物。类似地，铜基NC在通过A ³合成炔丙基胺中表现出相当好的催化效率（> 80％）。苯乙炔与各种醛和胺的偶联反应。重要的是，这些NC具有良好的可重用性，在几个循环后效率没有显着降低。但是，与大多数已报道的类似催化剂相比，设计的NCs的主要优点是Pd或Cu含量较低（分别为1.5 wt％和2.6 wt％）（Pd介于3 – 6 wt％和> 5 wt％对于铜），这是一个关键挑战，因为要开发具有成本效益和环境友好的催化剂，同时保持高效率。