Hydrogels mimic the tissue environment because of their hydrophilic and porous network structures. They are widely investigated in biomedical and biotechnological fields, however, due to the poor mechanical properties and limited functions, their further applications are restricted. In order to tackle these problems, an emerging approach is focused on the development of nanocomposite hydrogels. Numerous nanoparticles, including carbon-based, silica, polymeric, and metal-based nanoparticles have been incorporated into hydrogels. The combination of the two different materials results in a hybrid material with synergistic properties of both components. Nanocomposite hydrogels are designed to possess superior physicochemical and biological properties. Therefore, they are rapidly developing new materials, which have predominant applications in biological and material sciences. In this manuscript, we intended to summarize recent development in the nanocomposite hydrogels and their applications in the biomedical field.

水凝胶由于其亲水性和多孔网络结构而模仿组织环境。它们在生物医学和生物技术领域得到了广泛的研究，但是，由于其较差的机械性能和有限的功能，其进一步的应用受到了限制。为了解决这些问题，一种新兴的方法集中在纳米复合水凝胶的开发上。包括碳基，二氧化硅，聚合物和金属基纳米颗粒在内的许多纳米颗粒已被掺入到水凝胶中。两种不同材料的组合产生具有两种组分协同性能的混合材料。纳米复合水凝胶经设计具有出色的物理化学和生物学特性。因此，他们正在迅速开发新材料，在生物和材料科学中具有主要应用。在本手稿中，我们打算总结纳米复合水凝胶的最新进展及其在生物医学领域中的应用。