Infection of bovine papillomavirus (BPV) has been associated with mucosal and/or cutaneous tumor development in bovids. To date, up to 27 genotypes of BPVs have been identified and classified based on the nucleotide sequence identity of L1 open reading frame. In the present study, the complete sequence of a novel BPV concurrently identified with BPV1 and BPV2 in the facial cutaneous papilloma lesion of a domestic cattle was characterized. The whole genome of the unclassified BPV was 7263 base pairs in full length with GC ratio of 42.9%. In comparison with published BPV sequences, L1 nucleotide sequence of the novel BPV shared 75% identity with BPV15, and was suggested to be classified in the genus, Xipapillomavirus. According to the criteria established by the International Committee on the Taxonomy of Viruses, the novel BPV was designated as BPV type 28.

牛乳头瘤病毒（BPV）的感染与牛的粘膜和/或皮肤肿瘤的发展有关。迄今为止，已经基于L1开放阅读框的核苷酸序列同一性鉴定并分类了多达27种BPV基因型。在本研究中，表征了在家牛的面部皮肤乳头状瘤病变中同时与BPV1和BPV2一起鉴定的新型BPV的完整序列。未分类的BPV的整个基因组全长7263个碱基对，GC率为42.9％。与已发表的BPV序列相比，新型BPV的L1核苷酸序列与BPV15具有75％的同一性，并建议归为Xipapillomavirus属。。根据国际病毒分类学委员会建立的标准，新型BPV被指定为BPV类型28 。