The mechanical properties (e.g. surface tension and bending modulus) of the cell membrane usually change when normal cells become cancerous, which opens up a way to diagnose cancer by detecting the vibration of the cell membrane. In this letter, we theoretically propose a highly sensitive method for the detection of cancer cells in terms of an all-optical domain. In the case of cervical cells, we find that cervical cancer cells have a peak shift of ##IMG## [http://ej.iop.org/images/1555-6611/30/8/085601/lpab9648ieqn1.gif] {$0.844 \mathrm{MHz}$} in the absorption spectrum compared with normal cervical cells. The results show that a peak shift can be detected in the absorption spectrum once the cells become cancerous. We expect that the proposed approach could advance the research in cancer detection.

中文翻译：

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全光学方案高度灵敏地选择性检测癌细胞

当正常细胞癌变时，细胞膜的机械性能（例如表面张力和弯曲模量）通常会发生变化，这开辟了一种通过检测细胞膜振动来诊断癌症的方法。在这封信中，我们从理论上提出了一种在全光学域方面检测癌细胞的高灵敏度方法。对于子宫颈细胞，我们发现子宫颈癌细胞的峰移为## IMG ## [http://ej.iop.org/images/1555-6611/30/8/085601/lpab9648ieqn1.gif]与正常子宫颈细胞相比，其吸收光谱中的{$ 0.844 \ mathrm {MHz} $}。结果表明，一旦细胞癌变，就可以在吸收光谱中检测到峰位移。我们希望所提出的方法可以促进癌症检测的研究。