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Erythrocyte depletion lifts nanoparticle half-lives.
Nature Biomedical Engineering ( IF 26.8 ) Pub Date : 2020-07-06 , DOI: 10.1038/s41551-020-0586-x
Horacio Cabral 1 , Kazunori Kataoka 2, 3
Affiliation  

The partial depletion of red blood cells via the administration of a low dose of anti-erythrocyte antibodies increases the circulation half-life of nanomedicines, as shown in rodent models of cancer.

中文翻译:

红细胞耗竭提升了纳米粒子的半衰期。

如癌症啮齿动物模型所示,通过给予低剂量的抗红血球抗体可部分清除红细胞,从而增加纳米药物的循环半衰期。
更新日期:2020-07-06
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