Abstract

Three new compounds, crotalariapallins A-C (1-3), were isolated from the 95% EtOH extract of the seeds of Crotalaria pallida. Their structures were established based on extensive spectroscopic methods, including HRESIMS, UV, 1D and 2D NMR. All compounds were evaluated for their inhibitory activities to tyrosinase. These compounds showed different degrees of inhibitory activities, among them, compound 3 exhibited the strongest inhibition activity (IC₅₀ = 0.42 mM).

中文翻译：

---

Crotalaria pallida 种子中抗酪氨酸酶化合物的分离及结构解析

摘要

从Crotalaria pallida种子的 95% EtOH 提取物中分离出三种新化合物 crotalariapallins AC ( 1-3 ) 。它们的结构是基于广泛的光谱方法建立的，包括 HRESIMS、UV、1D 和 2D NMR。评价所有化合物对酪氨酸酶的抑制活性。这些化合物表现出不同程度的抑制活性，其中化合物3表现出最强的抑制活性(IC ₅₀ = 0.42 mM)。