Inflammation is involved in cerebral ischemia/reperfusion (I/R)-induced neurological damage. Saikosaponin A (SSa), extracted from Radix bupleuri, has been reported to exert anti-inflammatory effects. This article aimed to investigate whether SSa could ameliorate neuroinflammation mediated by ischemic stroke and the underlying mechanism.

中文翻译：

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Saikosaponin A 减轻缺血/再灌注引起的神经损伤

炎症与脑缺血/再灌注 (I/R) 诱导的神经损伤有关。据报道，从柴胡中提取的柴胡皂苷 A (SSa)具有抗炎作用。本文旨在探讨 SSa 是否可以改善缺血性卒中介导的神经炎症及其潜在机制。